Soon CNCO performed at a popular music festival Vina del Mar, which is one of the most important events in the world of the Latin American music. The band was nominated for several categories of iHeart Radio Music Awards. At that time, many fans tried to book CNCO for private events, but they were often busy giving concerts.
In April 2017, the band released a new single for the upcoming album. The artists called the song “Hey DJ” and recorded it with the assistance with a singer Yandel from Puerto Rico. In August, they presented a remix for "Reggaeton Lento", recorded with a famous British group, Little Mix. The single became the second track for the upcoming LP. After some time, CNCO presented “Mamita”. It became a new hit, earning gold status in the USA.
After a short break, in March 2018, the artists presented a new song, "Mi Medicina". After its release, fans got a chance to pre-order the upcoming album. Then the band recorded “Bonita” and “Fiest en mi Casa”. Both singles got a music video. Each of the videos collected millions of views on YouTube. The group’s popularity was increasing with each released song.
In April 2018, the long-awaited second album came out. The new LP, CNCO, featured such hits as "Se Vuelve Loca", "Fiesta en Mi Casa", "Noche Inolvidable", "Estoy Enamorado de Ti", and many others. The album topped the Latin Music Chart and came in 33rd on Billboard 200. Sometime after the release, the boy band presented a new single “Solo Yo” and came up with another popular music video.